Types of Liquid Dosage Form

Liquid dosage forms are divided into two main parts, a) monophasic b) biphasic

a) Monophasic Liquid Dosage Form

Monophasic is a liquid dosage form that is comprised of a single-phase system. They

have a simple presentation, prepared by two or more dissolvable components. The monophasic liquid dosage form demonstrates rapid absorption at the site of action.

The monophasic liquid dosage form is known as a ‘True Solution’ which is a clear homogenous solution composed of a large medium ‘Solvent’ and a small-medium ‘Solute’.

Benefits:

Monophasic liquid dosage form is of prime importance such as

• The rate of absorption of the monophasic liquid dosage form is much greater than the solid dosage form. Because active pharmaceutical ingredient is already dissolved and available in the form of a solution.
• A monophasic liquid dosage form is homogeneous in nature; thus, it provides a consistent and accurate dose than a suspension or biphasic solution that requires strict shaking.
• The monophasic liquid dosage form can be administered by oral, parenteral, nasal, etc. routes efficiently.
• It is easy to swallow as compared to solid dosage formulations.

b) Biphasic Liquid Dosage Form
It is the type of liquid dosage form with a two-phase system. In biphasic liquid dosage form, a solid-state is dispersed into a ‘continuous phase’ that can be an aqueous or oil phase. A continuous phase is stabilized by a suspending agent.

A biphasic liquid dosage form is commonly used for the oral, parenteral, and topical routes.

Benefits:
Biphasic liquid forms certain benefits such as:

• A biphasic liquid dosage form has a high rate of bioavailability.
• Suspensions offer high action of a drug as solid particles are perfectly dissolved prior to absorption.
• Some drugs are not stable in the form of solutions such as Procaine Penicillin G. Therefore, they are administered in the form of suspension.