Top 11 Machineries for Manufacturing Pharmaceutical Tablets

Could your tablet manufacturing equipment be efficiently working for you?

Do you want to improve the quality of your tablet manufacturing production line?

Do you want to know the important machinery list used to produce and improve your production process?

There are advanced technologies emerged that offers the latest equipment with amazing features to increase production efficiencies in your manufacturing facility.

This review article is all about processing and tools implemented in the pharmaceutical tablet manufacturing process. Without wasting your precious time, let's get started it.

Pharmaceutical Tablets-1

Table of Contents

Ⅰ.Pulverizing Machine

Ⅱ.Vibration Sifter

Ⅲ.Roll Compactor/High Shear Mixer Granulator Wet Granulation

Ⅳ.Fluid Bed Dryer

Ⅴ.Grinding and Granulating Machine

VI.Mixing Machine

Ⅶ.Tablet Press Machine

Ⅷ.Tablet De-duster

Ⅸ.Tablet Coating Machine

Ⅹ.Tablet Counting Machine/Blister Packing Machine

XI.Cartoning Machine

Conclusion

Ⅰ.Pulverizing Machine

An essential type of size reducer used in pharmaceutical industries for crushing and grinding different coarse materials into specific sizes as required. It consists of a grinding chamber with different rotator speeds that result in size specificity.

High Efficient Pulverizing Machine

AIPAK  High Efficient Pulverizing Machine

1.Working Principle

Through a hopper or automatic rotary feeder, a crushing material is fed into a crushing chamber. The impact of strong hammers over the fed ingredients against the liner plates helps in making them into powders.

2.Benefits

  • The pulverizing machine operates with standardization and can easily be incorporated into the production processes.
  • The machines in pharmaceutical and non-pharmaceutical industries provide a size ranging margin for product development.
  • It is an energy-efficient machine and provides a broad range of products without blaring noise.
  • It has a dust-free design, easily avoiding dust contamination with reduced particles.
  • Another of the essential benefits of this machine is that its readily available worldwide and is economically affordable.

3.Applications

Pharmaceutical Industry:It is used for size reduction of particles which can be helpful to design appropriate dosage of the drug. It has significantly been worthwhile designing a solid dosage form such as tablets.

Pharmaceutical Industry

Food Industry:It grinds dry particles into the finest, more straightforward form, such as grinding spices and animal feed.

Food Industry

WoodIndustry: In wood industries where the forest wood is crushed for a different purpose, the pulverizing machine plays a vital role in crushing wood.

Wood Industry

Limestone & Coal Industry:Pulverizing machines can also help grind coal and limestone further delivered to other industries such as biomedical industries for various purposes.

Coal Industry

4.Why do you need a Pulverizing Machine?

A pulverizing, crushing, or comminution machine applies an external force on to the solid material and destroys its integrity, and reduces it into small pieces as compared to its larger sizes.

5.Next Step

When you get different sizes of small pieces then it is necessary to screen them according to the requirement of the protocol. There is not a specific standard specified for screening materials. Thus, the sifting or screening process is achieved using a vibratory sifter that ensures uniform particle size screening with help of a gyratory mechanism.

II.Vibration Sifter

A vibration sifter is a revolving vibratory sifting unit that is designed to ensure sorting, scale as well as scoring procedures for various industrial applications. This equipment is for you when you need separation, scalping, grading as well as processing material during tablet formation.

Vibrating Rectangular Screening Machine

AIPAK Vibrating Rectangular Screening Machine

1.Working Principle

The working principle of the vibration sifter is based on the gyratory vibration. Therefore, the material is separated due to different particle sizes.

2.Benefits

  • A vibration sifter is a compact machine present in portable designs.
  • This equipment is the best fit to manage dust particles.
  • The machine is safe and hygienic constructed with high-grade stainless steel.
  • High-speed operational services with the lowest noise production.
  • This machine ensures beneficial processes with easy to adjust mode.

3.Applications

Pharmaceutical Industry

For the formation of tablets, you must segregate the mass composition of various materials belonging from different states, for e.g.,  solid-solid, solid-liquid. For this vibratory sifter is frequently used in the pharmaceutical sector.

Pharmaceutical Industry-1

Food Industry

This machine is also highly applicable in the food industry for separate materials like flour (wheat, rice, corn). Furthermore, food preparatory firms extensively used vibratory sifter for the separation of lumps from the ingredients.

Food Industry-1

Chemical Industry

There are several chemical products accessible in the form of powders such as sodium chloride, magnesium sulfate, buffer salts, etc. Many of them are corrosive up to a certain extent.

A vibratory sifter is commonly used in the chemical industry for dealing such material to screen them into the finest form.

Chemical Industry-1

Fertilizer Industry

A vibratory sifter is an ideal machine for screening or sieving fertilizer granules. Besides this, for the production of pesticides, insecticides, and dyestuff, a vibratory sifter is of prime importance.

Fertilizer Industry

4.Why Do You Need a Vibratory Sifter?

You need a vibratory sifter machine for grading raw materials for the tablet manufacturing process. Vibratory sifters ensure the removal of aggregated lumps from powders and facilitate a particular size.

5.Next Step

After achieving the sifting process, the next step is to choose either roller compaction or high shear granulation to improve the physicochemical properties of powders.

In roller compaction granulation involves using dry binders, this process is particularly useful for those drugs that are moisture sensitive. While high shear mixer granulator wet granulation involved wet binder and produces more uniform mixing and content uniformity.

III.Roll Compactor/High Shear Mixer Granulator Wet Granulation

A) Roller Compactor

The granulation of particles using a roller compactor facilitates densification of a mixture when it is passing through a pair of rollers that offer a varied amount of pressure over pressing material and compact them. This procedure forms a ribbon that is milled to produce granules.

Roller Compactor

1.Working Principle
A formation of the ribbon by counter-rotating rollers ultimately results in the finest granules.

2.Benefits

  • Roller compaction is a traditional method that gives high binding and even content without using more binders.
  • No introduction of moisture content.
  • This is a simple and continuous process.
  • You don’t need to introduce heat or hot air.

3.Applications

Pharmaceutical Industry

A roller compactor is used in the pharmaceutical industry to agglomerate powders that contain active pharmaceutical ingredients and excipients ultimately combine to form uniform granules.

Pharmaceutical Industry-2

Food Industry

The roller compactor is designed to handle small- and large-scale production in the food industry to improve the bulk density of the powders.

Food Industry-2

Chemical Industry

Many chemical manufacturing process relays on the roller compactor to press the hard material between rolls due to pressure, friction, and compactness. For instance, coal, gypsum, plasticizer, etc.

Chemical Industry-2

4.Why Do You Need a Roller Compactor?

You need roller compactor machine in order to get powder with excellent flow properties.  Also, this machine is used to overcome particle degradation induced by wet granulation. For tablet formation, this machine ensures product stability, avoids particle segregation, overcomes the bulk volume as well as minimizes the storage volume.

5.Next Step

After achieving particle compaction and good uniformity in granules sizes. You select the grinding and granulating step for more homogeneity in mixing ingredients.

Grinding and granulating machines are ideal for this purpose that ensures elimination of larger particles that may affect the production process, as well as removes sticky particles make them uniform.

This machine helps you to enhance the particle uniformity that will improve the potency and efficacy of the drug.

B) High Shear Mixer Granulator 

A high shear mixer granulator is a widespread technique utilized in the formation of tablets, capsules, and other formulations. This is generally a shaping process where granules are formed using liquid binders that are speeded to the powders in a close and compact container that is comprised of blending tools as well as a chopper.

Series High-Speed Wet Mixing Granulator

AIPAK Series High-Speed Wet Mixing Granulator

1.Working Principle

The high shear mixer granulator wet granulation process takes place via agitation of mixing ingredients with the help of high-speed impellers.

2.Benefits

  • This procedure is most advanced and highly acceptable in the various industrial fields.
  • This machine ensures excellent granules formation without requiring extra binders.
  • This is a safe and secure machine that ensures suitable homogenization.
  • No dust formation occurs during the manufacturing process thereby lesser chances of cross-contamination.

3.Applications

Pharmaceutical Industry

A high shear mixer creates emulsions, suspensions, granular, and other medicinal products in the pharmaceutical industry.

Pharmaceutical Industry-3

Food Industry

High shear mixing ensures rapid mixing of all processing material in a very short time, thus highly popular in the food industry.

Food Industry-3

Chemical Industry

The high shear mixer offers ultra-high shear mixing and is commonly used in chemical process industries for manufacturing products.

Chemical Industry-3

Cosmetic Industry

High shear mixer inherent superior to stand blending properties thus offering uniform mixing, suitable for manufacturing creams, lotions, and facial products.

Cosmetic Industry-3

4.Why Do You Need High Shear Mixer Granulator Wet Granulation?

You need to manufacture tablets from smooth and uniform granules. This high-shear mixer is a forceful and excellent choice to get a suitable mixing process with ultra-high-speed impellers. This method is also known as the shaping process extensively used in pharmaceutical manufacturing departments to get dense granules.

5.Next Step

Now your ingredients hold some moisture content, so, would you like you to continue with further processes? Of course not! because it may weaken your product, its working effectiveness, and shelf-life.

You need to dry entire particles' content to get an incredible product. For this, a fluid bed dryer is an amazing machine that instantly dries your product required for flawless compression.

IV.Fluid Bed Dryer

A fluidized bed dryer is used to dry the pharmaceutical granules and powders by vaporizing excess moisture content in processing material through fluidization.

The main components of this equipment are:

  • Air preparatory unit
  • Exhaust filter
  • Control panel
  • Spray nozzle
  • Product container
  • Exhaust blower.
  • Air distribution plate
  • Solution conveying channel

Vibration Fluidized Bed

AIPAK Vibration Fluidized Bed

1.Working Principle

This equipment operates on the fluidization principle in which high-pressure hot air elevates the settled moist solid granules/particles to suspend them in an airstream (fluidized state) that allows heat transfer causing the material to dry by vaporizing liquid.

2.Benefits

  • It provides efficient contact between moist particles and hot gas, resulting in high moisture removal.
  • Thermal efficiency is high which is supplied by the internal heat exchanger.
  • Cost-effective operation and require minimal maintenance cost.
  • Rapid and uniform drying.
  • Control of setup is easy.
  • The temperature of the air inlet is adjustable and easy to control which allows an appropriate amount of moisture removal from granules/particles and prevents granules' surface crust that delays drying time.

3.Applications

Fluid Bed Dryer is widely used in a large number of industries such as; 

Pharmaceutical Industry: applied for drying powders, and granulesfor tablets and capsules production.

Pharmaceutical Industry-5

Chemical Industry:applied for drying extrudates, powders, crystalline materials such as salts, herbicides, detergents, polymers, plastics, fibers, metal salts, etc.

Chemical Industry-4

Food Industry:applied for drying dairy products (milk, coffee, powdered drinks, cereals, tea, starch, herbs and spices, and other related products).

Food Industry-5

Mineral Industry:applied for drying sand, silica sand, limestone, gypsum, kaolin, mineral ores, and other related materials.

Mineral Industry

4.Why do you need a Fluid Bed Dryer?

A fluid bed dryer is a popular equipment used for drying purposes in pharmaceutical and other manufacturing companies. This machine is widely used in the granulation technique for drying raw material in order to get anticipated moisture content in tablets.

5.Next Step

Grinding and granulating are generally applied procedures in the context of making materials small and smaller than a shredder.

You always need this technique at a high speed when manufacturing tablets. These machines are designed to give medium inertia, high-speed process with two to five steel knives. Read on next step to know more about this machine.

Ⅴ.Grinding and Granulating Machine

This equipment is used for processing solid materials such as milling, granules sizing, re-granulation of imperfect granules, and reproduction of powders from imperfect granules.

It is made up of the best quality stainless steel and fully satisfies current cGMP practices.

Grinding and Granulating Cone Mill

Grinding and Granulating Cone Mill

1.Working Principle

Processing material passes through the feed inlet of the machine and enters the conical sieve chamber. By the action of rotary knife and sieve mesh, granules are reduced into particles and released through the openings of the sieve.

2.Benefits

  • Provide continuous and rapid rotation of processing material to achieve efficient mixing.
  • Produce granules with good fluidity which leads to best tablet compression or capsule production.
  • Demand low use of adhesives that reduces the drying time in subsequent processes.
  • Offer rapid operation by allowing all processes such as grinding, dry mixing, wet mixing, and granulation in one sealed container.
  • Allow rapid, and safe grinding and mixing
  • Easy to clean and maintain.

3.Applications

Pharmaceutical Industry:High-demand equipment of the pharma industry. It is applied to blend numerous substances for granules production.

Pharmaceutical Industry-6

Cosmetic Industry:It is used for grinding, blending powders of beautifying herbs/ chemical ingredients to produce granules for tablets or capsules formulations.

Cosmetic Industry-5

Chemical Industry:Many chemicals remain stable in the granular form such as aluminum silicate, calcium hypochlorite, etc, therefore this machine is widely utilized in chemical industries.

Chemical Industry-5

4.Why do you need a Grinding and Granulating Machine?

For manufacturing tablets, this step is of prime importance. There are a variety of applications that require size reduction of granules, thus, grinding and granulation machines are important ways to get universal and reliable granulation of powders best fit for further process.

5.Next Step

Now we are moving to a crucial step in tablet formation, that’s mixing. Mixing plays an important role in the development and production of pharmaceutical tablets. That is why, a technology world has offered you uncountable mixers (solid-solid, solid-liquid, liquid-liquid, liquid-gas). Mixing enhances the quality of product via even distribution of active pharmaceutical ingredients and excipients.

ⅤI.Mixing Machine

This equipment is used for mixing drugs and excipients to form dosage forms. These ingredients can be in granular, powder form or in liquid form.

It increases the efficiency of mixing and produces a homogenous mixture by breaking the original composition of ingredients.

Numerous types of mixers are currently available depending on the type of substances they mix.

  • Agitator
  • Ribbon blender
  • Paddle mixer
  • Static mixers
  • Emulsifiers
  • Homogenizers
  • Drum mixer
  • Heavy-duty mixers
  • Tumble blender

Horizontal Ribbon Mixer

AIPAK Horizontal Ribbon Mixer

1.Working Principle

The function of the mixing machine is based on filling the mixer with processing ingredients at least half of its volume. Efficient and uniform mixing is achieved by the rotation of ribbon paddles and cylinders in the central axis.

2.Benefits

  • A high-quality clean process, allows minimal chances of contamination during operation.
  • Produce highly efficient, homogenous mixture.
  • Process bulk mass in less time, therefore increase
  • Allow mixing of immiscible liquids such as oil and water.
  • Environmentally friendly equipment, produces negligible amountsof dust.
  • Cost-effective process with less need of human resources.

3.Applications

Mixing machines is the core requirement of a number of industries such as;

Pharmaceutical Industry:It is used for mixing powders, granules to produce tablets, capsules, topical ointments, injectables, solutions, oral suspensions, and other dosage forms.

Pharmaceutical Industry-7

Adhesive and Sealant Industry:It is used for mixing chemicals, dyes, etc.

Adhesive and Sealant Industry

Agrochemical Industry:It is used for mixing animal nutritional ingredients, also used in the production of anti-pesticides and veterinary drugs.

Agrochemical Industry

Sewerage Company:It is used for cleaning and purification of contaminated water in which mixing is an essential process.

Sewerage Company

Cosmetic Industry:It is used for mixing ingredients that are utilized in the production of shampoos, moisteners, gels, and creams.

Cosmetic Industry

Paint Industry:It is used for manufacturing paints and coating solutions in which mixing is a key process.

Paint Industry

Food Industry:It is used for the production of juices, creams, desiccated milk products, and other related products.

Food Industry-6

4.Why do you need Mixing Machine?

Mixing is an important parameter that has net effects on the quality of the product. You can’t make a proper tablet or any pharmaceutical product if your mixing is insufficient.

As you need to keep your ingredients in an appropriate mixed form. Consequently, the mixer excludes the risk of triggering segregation, de-mixing, or unequal particle distribution in pharmaceutical dosage forms.

5.Next Step

After achieving the desired quality of particles size and improved flowability of powders, you need to compress them into a tablet with unvarying size and weight.
For this purpose, tablet press machines are available in the market that is extensively used in a broad range of industrial applications. Read on to the next step to find more about this machine.

Ⅶ.Tablet Press Machine

It is mechanical equipment that is widely used for tablet formation of constant shape, size, and amount of drug (API) plus excipients. It forms tablets by applying compression force.

A tablet press is alternatively called a tablet punching machine, tablet compressing machine, and pharmaceutical tablet press.

Mainly available in two types. However, various models of different brands are available that differ in speed, size, and capacity.

  • Single punch machine
  • Multi-station/rotary machine

High Speed Tabet Press

High Speed Tabet Press

1.Working Principle

The entire process is dependent on a set of two punches and a die. The die contains a fixed amount of powder mixture/granules which is compressed by an appropriate compression force exerted by the upper and lower punches.

2.Benefits

  • Available in multiple models as per user requirements, such as single punch press for small-scale production and rotary press for large-scale production ( up to 234000 tablets per hour).
  • High- throughput, cost-effective, and time-saving operation.
  • Operation and maintenance are easy.
  • Single punch press can also produce tablets of uncommon shapes and sizesof up to 20mm diameter.
  • The hardness and weight of tablets can be individually controlled in the rotary press.

3.Applications

Tablet compressing machines are widely used in the following industries.

Pharmaceutical Industry:It is considered as the core equipment in pharma industries for small- and large-scale tablets batch production.

Pharmaceutical Industry-8

Research and Development (R&D) Laboratory:It is highly applicable in R&D labs of universities and industries for experimentation on tablets.

Research and Development

Herbal Industry:It is applied for the production of tablets from crushing plants.

Herbal Industry

Ceramic Industry:It is applied for the production of parts of multiple shapes and sizes.

Ceramic Industry

Chewable Tablets Production:It is applied for manufacturing chewable tablets which contain ingredients that differ from common tablets such as flavors, lubricants, mannitol, binders, and others.

Chewable Tablets Production

Effervescent Tablets Production:It is used for manufacturing effervescent tablets which contain special ingredients such as sodium bicarbonate, citric acid, and tartaric acid.

Effervescent Tablets Production

4.Why Do You Need a Tablet Press?

A tablet press machine can deal thousands of tablets per hour and is designed to ensure an incredible output, suitable for small as well as large batches.

A tablet press compresses powders typically uses a punch head and other accessories for compression. This machine plays a fundamental role in tablet formation and competitively keeps your production process going on.

5.Next Step

Tablets are not packed or marketed after obtaining from tablet press. Though, you will be having to pass them from other processes to enhance their aesthetic look and protection.
Yes, we’re indicating an important tool name a tablet deduster, that ensures a dust-free tablet upon treating.

Ⅷ.Tablet De-duster

Tablet Deduster is equipment that works next to tablet press in the production line of pharmaceutical industries. It helps in cleaning the surface of compressed tablets by removing fine particles/dust through vibrations.

Many types of tablets deduster are available with distinctive features such as;

  • Uphill tablet deduster
  • Brush type tablet deduster
  • Rotary vibrating tablet deduster
  • Vertical upward/ downward conveying tablet deduster
  • Horizontal tablet deduster

A tablet Deduster Machine

A tablet Deduster Machine

1.Working Principle

The vibratory motion which is produced by the mechanical force is the basis of the tablet deduster function. Vibratory effects allow the lifting of tablets in an upward direction in order to dedust and polish them at once. Mechanical force is generated by the electromagnetic vibrator and the whole process is dependent on the charge/discharge of the electromagnetic coil.

2.Benefits

  • This machine offers several benefits to the tablet production process.
  • Highly efficient, safe, and gentle polishing and dedusting process thatcauses minor or no damages to the tablets.
  • Adjustable machine and can be linked to any tablet press in the production line.
  • Adaptable height, movable equipment, and easy to clean.
  • Made with advanced technology, therefore, satisfies compliance with Current Good Manufacturing Practices (cGMP).

3.Applications

Pharmaceutical and Nutraceutical Industry:Tablet deduster is widely used for cleaning dust on tablets and capsules in pharmaceutical and nutraceutical industries.

Dust on tablets is a combination of unwanted powder and burrs which interrupts subsequent processes of the production line such as packaging, therefore, required to be eliminated.

Additionally, it is also utilized for,

  • Lifting/elevating of tablets
  • Polishing of tablets
  • Movement of tablets

Pharmaceutical and Nutraceutical Industry

4.Why Do You Need a Tablet Deduster?

A tablet deduster is an advanced machine extensively used in every pharmaceutical production department. This machine helps in cleaning, dedusting, and polishing tablets. Hence it improves the branding of your business by offering smooth, cleaned, and radiant tablets.

5.Next Step

To mask the bitter taste, enhance the appearance (colors, luster), improve texture, protection, etc., you must need a tablet coating machine. This is one of the essential steps for the preparation of tablets. Your production line won’t be ideal if a tablet coating machine is not there. Let's read on the next step to know more about this incredible machine.

Ⅸ.Tablet Coating Machine

It is important mechanical equipment of the tablets production line that coats a dry, thin layer on the outer rough surface of tablets by a coating solution or suspension.

Many models of tablet coating machines are available, however, all of them are based on the following three main types.

  • Perforated coating pan
  • standard coating pan
  • Fluidized bed or air suspension coating pan

High efficient Film Coating Machine

AIPAK High-efficient Film Coating Machine

1.Working Principle

This machine uniformly applies a coating solution on a large number of tablets that are moving vertically or horizontally in the coating pan. The excess solvent of the coating solution is evaporated by the concurrent hot air stream in the coating pan.

2.Benefits

  • Tablet coating machine offers many benefits to the tablet production process such as;
  • Provide rapid and uniform distribution of coating solution with an atomizer.
  • Can be used for both film and sugar-coating methods.
  • The drying process is highly efficient andreduces overall coating time.
  • Many airflow alignments can be fixed in the perforated coating pan
  • Highly precise, uniform, and thin coating can be achieved with dual spray-atomization systems in a fluidized bed coating pan.

3.Applications

Tablet coating machines are widely applicable in pharmaceutical industries for improving the quality of tablet formulation. It serves many purposes such as:

Modified Drug Release Formulations:This machine is utilized for producing modified drug release formulations such as sustained and delayed drug release dosage forms. By using various polymers for thin coating, the drug release site and rate can be modified to increase drug efficacy, duration of action, and patient compliance.

Modified Drug Release Formulations

Improved Drug Stability:Tablet coating protects the drug from physical and chemical decomposition such as it protects drugs from light and moisture exposure.

Improved Drug Stability

Taste Masking: Tablet coating can mask the unpleasant taste, color, and odor of drugs.

Palatability:Tablet coating provides a smooth surface which increases drug palatability.

Appearance:Coating on tablets results in a smooth and even colored surface which increases the visual appearance and patient compliance.

Appearance

4.Why Do you Need a Tablet Coating Machine?

You need a tablet-coating machine for two important purposes. First, for decorative reasons, the coating is done to achieve good color, glossiness, and mask the bitter taste of the manufactured tablet. Second, you can protect the tablets from physical and chemical degradation by applying a coating on them. A coating machine is a simple system that can execute this job by unfluctuating spraying of coating matter effectively.

5.Next Step

This machine is almost utilized when you’ve done tablet manufacturing, dedusting, and coating. Counting the tablets is a significant task that demands an easy solution.

Because you can’t do this job manually; this era of advanced technology has to offer you a simple solution in the form of automatic tablet counters.

This machine has the capability to integrate with a blister packing machine for the final packaging procedure.  Read on to the next step to learn more.

Ⅹ.Tablet Counting Machine/Blister Packing Machine

(A) Tablet Counting Machine

This machine helps in counting the tablets before packaging in pharmaceutical or other related industries. This machine is well equipped with many parts however, the main parts are the container, conveyor tracking, electromagnetic vibrating plate, and micro screen. 

Automatic Tablet Counting Machine

AIPAK Automatic Tablet Counting Machine

1.Working Principle

The operation of the tablet counting machine is based on photoelectricity induction that helps in counting, delivery of tablets in bottles, and adjustment of setup parameters. This machine utilizes vibratory movements to automatically count tablets which are placed in 24 adjustable “V” (vibrated)-shaped grooves.

2.Benefits

  • Operation is easy and based on three buttons; start speed control and emergency stop.
  • Provides accurate counting of tablets (~ 99.5 to 99.9 %) and also alertsthe user about damaged tablets.
  • Cost-effective, rapid, and highly precise operation.
  • Equipped with cameras/sensors that detect errors in the machine and in the tablet formulation.
  • Well-equipped reduces chances of product contamination.
  • Minimal changeover time in processing different products. Changeover refers to a step of switching a machine operation from one product to another.
  • Durable equipment with convenient cleaning and maintenance features.
  • Available in different models as per user requirements.

3.Applications

Tablet Counting Machine is utilized in many industries/departments that include;

Retail Pharmacy:Accurate dispensing of tablets in retail pharmacies requires a tablet counting machine on a daily basis.

Retail Pharmacy

Pharmaceutical Industry:It is considered as the main equipment of the tablet production line, required for accurate counting, packaging, and detecting errors in tablet formulation.

Pharmaceutical Industry-9

Veterinary Hospitals:Similarly, it is utilized in veterinary hospitals for counting, packaging, and detecting errors in veterinary tablet dosage form.

Veterinary Hospitals

Cosmetic Industries:It is also applicable for counting cosmeceuticals tablets.

Cosmetic Industries

Hospital System:Required for accurate dispensing of medicines for optimal patient care in hospital systems including physicians’, dieticians’ clinics, mental hospitals.

Hospital System

4.Why Do You Need a Tablet Counting Machine?

A tablet counting machine ensures you an accurate, rapid, and reliable output with 100% counting accuracy. That is why, a tablet counting machine is considered as an ideal solution in eliminating the broken tablets, bulk counting per hour, and free from dust sensitivity.

5.Next Step

To make things crystal clear, protective, and easy to dispense, blister packing is used. A blister packing machine offers an air-tight sealing to your products that guarantees to improve the tablet’s integrity, temper-evident and immobilized. Blister packaging machines are available in many types suitable for small laboratories to large production lines.

(B) Blister Packing Machine

A blister packing machine is utilized for packaging of unit-dose of tablets. It consists of a cavity or a bubble pack (composed of a formable film of aluminum or thermoformed plastic material) that is sealed on top with aluminum foil.

Blister packs are of three types based on material types and the method by which it is formed.

  • Aluminum/plastic/aluminum bubble pack
  • Aluminum/aluminum (cold forming) bubble pack
  • Aluminum/plastic (thermoforming) bubble pack
  • Furthermore, blister packing machines are of three types based on their operation.
  • Roller type blister packaging machine
  • Flat plate blister packaging machine
  • Roller plate blister packaging machine

 Aluminium PVC Flat Plate Blister Packing Machine

AIPAK Aluminium PVC Flat Plate Blister Packing Machine

1.Working Principle

This machine works on an electromechanical principle that is dependent on the function of both stationary and moving parts. These parts work together to package and seal the tablets by heat in pre-formed cavities.

2.Benefits

  • Producesair-tight seal on tablet blister pack hence, preserving tablet integrity by preventing drug decomposition with time.
  • Cost-effective, low cost comparedto plastic packaging.
  • Providesa unit-dose pack that helps patients in tracking their administered medicine records.
  • Helpsin easy identification of tablets due to clear, and complete labeled information on blister packs.

3.Applications

Blister packing machines are widely applicable in the following industries.

Pharmaceutical Industry:Fundamental requirement of pharmaceuticals industries, it is used for packing capsules, tablets, and lozenges in unit-dose.

Pharmaceutical Industry-10

Research and Development (R&D) Laboratories:Highly applicable in (R&D) labs for stability testing, clinical trials, and package development.

Research and Development-2

Medical Tools Manufacturer: It is used for producing medical blister trays for packing medical tools/devicesthat differ from tablet blister packs due to their firmness.

Medical Tools Manufacturer

Food Industry:Applied in food industries to preserve food because it produces air-tight seals on food products that prevent exposure to heat and moisture.

Food Industry-8

Consumer Goods Industry:Applied for packaging electronic products, hardware materials, toys, and stationery products.

Consumer Goods Industry-8

4.Why do You Need a Blister Packaging Machine?

A blister packing machine is used to keep freshness, originality, dosage size, product appearance, visibility, and security of the product. Blister packing keeps your tablets in potent and efficacious form. This is a simple machine where all the functions are performed automatically. That’s why you can’t ignore this machine for creating durable, and consistent packaging.

5.Next Step

For all fast-moving goods sector; such as pharmaceuticals, foods, cosmetics, etc, cartoning machine is used. The types of cartoning machines are varying depending upon the scale of the business.

Here we need to fix the loaded tablets for their final step utilizing the cartoning machine.

This machine is capable to handle many types of cartons such as small, medium, and large sizes.
Want to know more? read on our last step of the tablet manufacturing process.

XI.Cartoning Machine

Cartoning machine is used for packaging small unit blister pack boxes into a large box and facilitating transportation of medicines globally without losing product integrity.

Based on function, cartoning machine is available in two types;

  • Automatic
  • Semi-automatic.
  • Based on orientation, it is also available in two types;
  • Horizontal cartoning-machine
  • Vertical cartoning-machine

Horizontal Boxes Packaging Cartoning Machine

AIPAK Horizontal Boxes Packaging Cartoning Machine

1.Working Principle

Three inlets are required for feeding packages into the carton machine; the machine box inlet, the vial inlet, and the instruction inlet. The process is based on fixing and opening the tray, filling packages into the carton in the loading area, folding of right and left ears, and finally capping and closing the carton.

2.Benefits

  • It offers time-saving, cost-effective, and highly efficient operation.
  • Applicable on both chipboard-made small and medium-sized cartons.
  • Operation is fully mechanical in automatic cartoning machines.
  • Helps in the transportation of large numbersof products in small spaces.

3.Applications

Food Industry:Applied for packaging pastries, biscuits, meals, seeds, grains, chocolates, and sweets.

Food Industry-10

Pharmaceutical Industry:Applied for packaging bottles, medical tools, capsules, sachets, vials, tablet blisters, and other related cosmeceuticals products.

Pharmaceutical Industry-12

Cosmetic Industry:Applied for packaging bottles, capsules, sachets, vials, tablet blisters, and other related cosmeceuticals products.

Cosmetic Industry-12

4.Why Do You Need a Cartoning Machine?

An automatic cartoning machine is beneficial for tablet packaging as it executes the entire production line automatically. Hence, this machine is cost-effective and provides a high-quality-controlled output. This machine is of prime importance as it boosts up the company profile by improving standard products at very low market expenditure.

Conclusion

We summarize and demonstrate common pharmaceutical tablet manufacturing machineries to our readers. If you’re a seasoned professional or a newbie in the world of the pharmaceutical tablet manufacturing process. We recommend you opt AIPAK Pharmaceutical Equipment to build an advanced technology production line.

We are here to assist you to choose the right machine that guarantees an improved product line. Click HERE to find our free consultation, User Guidance, and Machine Quotations.

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