How Does The Filling Weight And Tablet Weight Affect The Tablet Manufacturing Process?

1.What Is Tablet Manufacturing Process And Tablet Pressing Machine?

Tablet Manufacturing Process-Sourced:lohmann-minerals

Tablet manufacturing process refers to the whole process which involves the tablets material preparing, tablets making and so on. Tablet manufacturing process obeys the strict processing role and hygienic standard. It promotes the manufacturing of qualified and great tablet products.

Tablet pressing machine is the machine which is particularly applied for the manufacturing of tablets products. It can perform a series of work like powder filling, tablet pressing, tablet ejecting and so on. Besides, there are tablet pressing machines with different type and different feature for your different manufacturing demand.

2.How Can Tablet Pressing Machine Benefit You?

How can tablet pressing machine benefit you? Here are the main advantages of tablet pressing machine.

High efficiency

High Efficiency-Sourced:smpnutra

Tablet pressing machine is highly efficient. The high speed operating can handle the large scale tablet production in a short time. It can save your time and energy and makes great benefits for your business. And for various tablets type, it is flexible and almighty.

Quality prove

Quality Prove-Sourced:gea

Tablet pressing machine makes sure the quality of your tablets products as it makes the accurate and precise work. The tablet pressing machine makes sure the even and uniformity of your tablets products. And for the tablets of different shape and square, it can also prove the quality.

Easy to operate

With the simple parameter sending and easy operating, the machine can begin the tablet pressing work. It saves the energy of training operator and saves the budget and time you spend on operation. The operating interfaces is clear and you can make the great operating.

High flexible

Tablet pressing machine is flexible enough to handle the various types and size of tablet products. The high flexibility saves your budget in making different tablets and you can make the various types of tablets with the simple machines.

Hygiene prove

Hygiene Prove-Sourced:nutraceuticalbusinessreview

You may have the hygiene and safety proved with your tablet pressing machine. The manufacturing of your tablets makes the least joining of labor and makes sure the hygiene of your products. You may thus have the high qualified and hygienic tablets products.

3.How Does The Filling Weight And Tablet Weight Affect The Tablet Manufacturing Process?

How does the filling weight and tablet weight affect the tablet manufacturing process?

Theoretical quantitative relationship

In an ideal situation, according to the law of mass conservation, the fill amount equals to tablet weight. That is, the total amount of material added to the tablet press mold will be fully converted into the weight of the tablet after the tablet compression process. Assuming no material loss, if the fill amount is 500mg, the final tablet weight should theoretically also be 500mg.

Interactions in actual production

Fill amount determines tablet weight

Tablet Weight-Sourced:medicalnewstoday

In actual production, the fill amount is the key factor determining tablet weight. By adjusting the filling device of the tablet press and changing the fill amount, the tablet weight will change positively. For example, when producing acetaminophen tablets, if the fill amount is adjusted from 300mg to 350mg, the tablet weight will increase accordingly.

Tablet weight feedback adjusts fill amount

To ensure accurate drug dosage and stable product quality, tablet weight needs to be monitored and controlled in real time. Once the tablet weight deviates from the standard range, the fill amount needs to be adjusted promptly. For example, if a batch of tablets requires a weight of 250mg, and an inspection finds the weight to be 260mg, the fill amount needs to be appropriately reduced to ensure that the subsequent tablets meet the standard weight.

Factors affecting the relationship between fill amount and tablet weight

Material properties

Material Properties-Sourced:azom

Flow

Materials with good flow can be uniformly and smoothly filled into the mold, resulting in stable fill amounts and smaller tablet weight variations. Conversely, materials with poor flow can cause uneven filling, leading to fluctuations in tablet weight. For example, micro-powdered silica has good flow and can improve filling performance and stabilize tablet weight when added to materials.

Compressibility

Materials with good compressibility are easily formed under pressure, resulting in heavier tablets at the same fill amount. For instance, lactose has good compressibility, and when used as a filler, it can produce tablets with appropriate weight and good hardness at a certain fill amount.

Equipment factors

Equipment Factors-Sourced:loynds

Filling device accuracy

The accuracy of the filling device directly affects the accuracy of the fill amount, which in turn impacts the tablet weight. High-precision filling devices can control the fill amount within a smaller error range. It can thus ensure stable tablet weight.

Die and punch wear

Over time, the punches and dies may experience wear, causing changes in the mold dimensions, which can affect the fill amount and tablet weight. For instance, if the inner diameter of the die increases, the thickness of the tablet may decrease with the same fill amount, leading to a lighter tablet weight.

4.What Are The MainParts Of Tablet Pressing Machine?

Tablet pressing machine is not a complex machine. And here are its main components. The knowing of these components can help you know the machine better.

Hopper

AIPAK Hopper

Hopper is the part of tablet pressing machine which lead the raw material to the tablet pressing machine. It may sometimes corporate with other filling machine for the smooth and efficient tablet pressing work. The hopper is made of stainless steel and can prove the safety and hygiene of your tablets raw material.

Feeder system

Feeder System-Sourced:piab

Filling is the important process of tablet pressing work. Feeder system makes the precise and careful measuring of the powder weight for the tablets products. It can fill the according amount of weight of powder into the mold with your instructions. You can also adjust parameter for different tablet products need.

Press punches

Press Punches-Sourced:osdmachinery

Press punches makes the important work of pressing tablets with various types of powder. For a tablet pressing machine, there will be various punches and die for you to choose. And you should adopt the punches according to your products need. The precise and powerful punches can corporate with die system to make the even and qualified tablets products.

Tablet press turret

Tablet Press Turret-Sourced:eliz

Tablet press turret is the important part of die system. It makes the necessary work of aligning punches and die. In the tablet pressing system. There will be problem in pressing process for the no applying of tablet press turret.

Ejection system

For the whole tablet pressing system, ejection system is the last step. After the pressing of the tablets products, there will be ejecting parts for the safe and efficient ejecting of your tablets products. Ejecting system makes the last step of tablet pressing process and should pay great attention to.

5.What AffectOperation Of Your Tablet Pressing Machine?

For your tablet pressing machine work, there will be some factors which may affect the efficiency of the whole process.

Machine condition

Machine Condition-Sourced:avetechnologies

The great machine condition can of course make the better tablet pressing work. The worn machine parts, residues affect and many other parts can all lead the low efficiency or low products quality of your tablet pressing machine. You should make the regular cleaning and check the machine condition to prove the great work of your tablet pressing machine.

Mold adjusting

Mold Adjusting-Sourced:korsch

The suitable mold can improve the efficiency of your tablet pressing machine. You should choose the mold according to your tablets products feature. The suitable products molding can make the high qualified products. Your products can then be more even and the operating efficiency will be faster.

Parameter setting

You should make the right setting of the parameters of your tablet pressing machine. The suitable parameter which suits the tables feature can benefit your tablets pressing manufacturing.

Machine supporting

For the high efficient machine operating work, you may also seek other machines for help. The support of filling machine, blender machine and later packing machine can save your energy in making the tables and also prove the quality of your products.

6.What Machine You Should Apply For Your Tablet Pressing Machine Supporting?

The corporation with other machine can improve the efficiency of your tablet pressing machines. And here are some machines which can corporate with tablet pressing machine.

Bin mixer

AIPAK Bin Mixer

Bin mixer is the kind of machine which can make the high efficient and even blending of various types of powder. For tablets products manufacturing, even powder is inevitable and is the base for your high qualified tablets products.

Fluid bed dryer

AIPAK Fluid Bed Dryer

Fluid bed dryer makes the great job of making the even and dry powder. It can also makes the granulating and coating job. For the tablets with high request on powder or granules quality, fluid bed dryer makes the inevitable work for tablet pressing machine work.

Tablet coating machine

AIPAK Tablet Coating Machine

Coating is a great choice for your tablets if you have the request of better protection, taste and longer shelf life. Tablet coating machine can make the even and reliable coating for various types and shape of tablets products.

Tablet counting machine

AIPAK Tablet Counting Machine

Tablet counting machine makes the precise and efficient coating for your tablets number. You can make the relative setting for your tablets number and then wait for the coming of the right number of tablets in your bottle. It can make the counting and bottling in the same time.

Blister packaging machine

AIPAK Blister Packaging Machine

Blister packaging machine is the machine which can make the quick and efficient blister packing for your tablets. And there you can also choose the different blister machine type for your different blister packing need.

Cartoning machine

AIPAK Cartoning Machine

Carton packing is the last step and also the most important step for your tablets production line. Carton can make the better protection for your tablets products. Here are the cartoning machine which can handle various products. And with the attracting carton, your products will be welcomed by more and more customers.

7.What You Should Consider While Buying Your Tablet Pressing Machine?

Tablet pressing machine is inevitable for your pharmaceutical industry. For the purchase of the real nice one, come on and have a reading of this buying guide.

Production need

Production Need-Sourced:goodrx

You should first know your production need for the selection of your machine purchase. The production scale is the first factor you should consider as it makes the request for your machine type and production scale. You should also make sure your products type and choose the machine according to tablets material.

Machine capacity

Machine capacity refers to your machine performance, production ability and so on. Here are also tablet pressing machine of different automation level for you to choose. You should choose your tablet pressing machine’s machine capacity according to your budget, manufacturing need and so on.

Industry standard

Industry Standard-Sourced:callcentrehelper

For different country and place, there is different qualification standard for your tablet manufacturing process. And you should choose the tablet pressing machine which suits your local standard. The suitable one can make the benefits for your later tablet pressing work.

Maintaining difficulty

The maintaining can also affect your later manufacturing process. The machine with low maintaining difficulty can make great benefits for your business. It can have your energy and cost in machine maintaining reduced greatly.

Manufacturer reputation

Manufacturer Reputation-Sourced:ishn

The market of tablet pressing machine is big. And for the reliable machine choose, you should make the comprehensive inspecting for the various machine manufacturer. The one with great reputation can make the reliable consulting service and after-sale service.

8.Why There Is The Rapid Growth Of Tablet Pressing Machine?

You may have seen the rapid growth of tablet pressing machine in market. Have you ever wondered the reasons?

Stricter regulations

Stricter Regulations-Sourced:international-adviser

There is the stricter request on tablets manufacturing for the prove of tablets quality and safety. The changing regulation on tablets pressing manufacturing promotes the advancing of tablet pressing machines. The stricter regulation of tablet pressing machine promotes the making of more advanced tablet pressing machines.

Technology developing

There is the fast growing of tablet pressing technique in world. And with the fast growing, there is the innovation on tablet pressing machine manufacturing. The fast technology developing makes the higher automation level, better performance and higher efficiency.

Market request

Market Request-Sourced:contentsnare

In current pharmaceutical market, there is the trend of customized tablets, creative tablets and eco-friendly tablets. And the tablet pressing machine for tablets manufacturing should also be updated. The changing and high requested pharmaceutical market promotes the developing of tablet pressing machine.

Cost saving

Cost Saving-Sourced:inc

The money saving is also the factor which promotes the developing of tablet pressing machine. The new tablet pressing machine can help save your budget and money as it is more efficient and more energy saving. This can also promote the rapid growth of tablet pressing machine.

9.What Qualification Standard Tablet Pressing Machine Should Conform?

Tablet pressing machine makes great impact for tablets quality and safety. And the conforming of the below qualification standard is important.

TSM standard

TSM standard refers to tablet specification manual which is widely accepted in the United States. It is the only manual which makes the clear and strict standard for tablet pressing industry. This standard is widely accepted in the United States and promotes the manufacturing of the high qualified pressed tablets.

EU standard

EU Standard-Sourced:ecosistant

EU standard refers to European Standard which is also the widely welcomed standard in world. It makes the request on the tablets tooling and mechanism. This standard makes the efficient regulation for tablets pressing and tablets tool applying. EU standard circulates in many places.

cGMP standard

cGMP Standard-Sourced:profacgen

cGMP standard makes the request on the manufacturing process, machine technique and so on for your tablets manufacturing process. It makes sure the current great manufacturing practice for your tablets pressing work.

Conclusion

How does the filling weight and tablet weight affect the tablet manufacturing process? Do you have your own answers? Tablet pressing machine is so helpful and intelligent which can make great benefits for pharmaceutical industry. If you want to know more or have any problem or question about tablet pressing machine, contact AIPAK now!