How Can Mixed Granulator Machine Develop In The Market For A Long Time?
In the tablet production process, mixing and granulation are important steps before tabletting. It is understood that for a long time, most pharmaceutical factories still use traditional trough mixers and rocking granulators for mixing and granulation in tablet production.
The traditional trough mixer relies on the S-shaped stirring paddle to stir at low speed to mix the powder. The type granulator machine is to extrude the mixed powder into strips, and then cut into granules by a cutter.
Because the granules made have water chestnuts, the fluidity is poor, and there are partial stacking and bridging phenomena during tabletting. The accuracy of feeding is poor, so the extruded tablets have problems such as loose tablets, fragments, and different tablet weights
Under the background of the current rapid development of the pharmaceutical industry and the increasing market scale, the mixing and granulation equipment urgently needs to be upgraded and transformed.
The wet mixing granulator machine is a kind of solid preparation pharmaceutical equipment that has developed rapidly in recent years. The process combines the two-step process of mixing and granulation, which not only saves time, but also meets the requirements of GMP and reduces cross-contamination.
The efficiency is improved, which is a method that is much faster and more economical, and is very popular among customers. It is reported that the wet mixing granulator machine improves production efficiency, saves labor costs, and makes tablet production more scientific and stable.
The wet granulator is an ideal equipment for capsule production.
According to the analysis of relevant technical personnel, the wet mixing granulator machine adopts the inverted conical granulation integrated pot technology and special switch stirring paddle and cutting knife in structure so that the material can be rolled evenly and ensured.
The granulated product is more uniform and reliable. The bottom of the tank is an inter layer, with a built-in water cooling circulation system, the constant temperature performance is better than that of the general air cooling system, and the quality of the particles is improved.
Both the stirring paddle and the cutting knife adopt frequency conversion speed regulation, which is easy to control the particle size to meet the diversity of pharmaceutical processes. Compressed air is used to seal the drive shaft, eliminating the phenomenon of dust adhesion.
It can be switched to purified water during cleaning, which can be cleaned automatically; with a paddle lift system, it is beneficial to clean the paddle and the pot.
The lid of the pot is automatically lifted, and the discharge port is matched with the drying equipment. The large model comes with an escalator, which is easy to operate. The discharge port is arc-shaped to prevent blind angle.
The industrial professional said that at present, companies basically import Glatt or GEA series granulation equipment from abroad which comes from Germany. There is a big gap in the equipment market of China, which needs to be deeply cultivated.
The experts said that the performance of the wet granulator mainly depends on the sealing method and sealing effect of the cutter and stirring paddle. The equipment with poor sealing effect is easy to enter dust. Even if it can be cleaned online, it is easy to cause water to enter the reduction box and affect the production and use of equipment.
In addition, in terms of humanized design, the mixing granulator machine equipment manufacturer needs to design the gap between the paddle and the bottom of the pot when producing the equipment to facilitate unloading and cleaning.
At the same time, it is necessary to pay attention to the ease of disassembly of the paddle and the cutter to ensure the disassembly effect of the paddle and the cutter.
The experts also said that the wet type selection must be chosen according to the product, and the shape of the paddle should be selected according to the shape of the product.
The large shear force is good, but if some traditional Chinese medicines use large shear force in the process of clearing the paste, it will be difficult. There may be situations such as sticking to the pan and not being easy to shake.
Judging from the current development of the tablet industry, the frequent introduction of policies in the pharmaceutical field and the continuous growth of market demand, the tablet industry is facing a new round of structural adjustment while ushering in great development prospects.
The technology of granulator machine and mixing equipment is also in urgent need of upgrading, and products are in urgent need of upgrading. In this update, how to make breakthroughs in the domestic granulating mixer equipment industry is the key to challenging foreign imported equipment.
According to industry professionals, domestic mixing and granulating equipment needs to develop enterprises and enhance competitiveness with a pragmatic attitude through independent innovation and deep digestion.
Continue to catch up with foreign advanced pharmaceutical machinery technology, opening up a new world for my country's pharmaceutical equipment industry.
Preparations play a role in linking the past and the future in the pharmaceutical industry chain. They can not only support the research and development of new drugs, but also help the final industrialization of new drugs.
Granulation is an important part of the solid preparation pharmaceutical production process, and the selection of a reasonable granulator machine is of great significance for the development of enterprises.
The wet granulator machine fully ensures that the granulated product is more uniform and reliable. With the development of the pharmaceutical industry, the wet granulator machine will play a major role.
However, from the current point of view, the wet granulator machine still has certain defects. Therefore, relevant companies still need to continue to make efforts to strengthen the innovative research and development of equipment and produce more products to promote the steady development of the pharmaceutical industry.
With the rapid development of automation and intelligence, the transformation speed of the granulation equipment industry will continue to accelerate.
Only by keeping up with the pulse of the market and strengthening learning, absorption and innovation can pharmaceutical machine companies ensure that the equipment will not be eliminated in the market and occupy a place.
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