4 Things That You Need To know About Crusher Machine

The emergence of crusher machine is a major breakthrough in the development of the pharmaceutical industry. It not only greatly improves the production efficiency of pharmaceuticals, but also makes the dosage more accurate, the efficacy better, and the patients can get better protection.

There are many opinions about the modernization of traditional Chinese medicine, which can be summed up into three viewpoints: first, Western medicine should be used to westernize traditional Chinese medicine, that is, traditional Chinese medicine should be western medicine; Second, maintain the independent development of traditional Chinese medicine; Third, to maintain the traditional advantages and characteristics.

Chinese and western medicine learn from each other, complement each other's advantages, according to their own way of thinking, the use of advanced science and technology, to seek their own path of development. In the process of modernization of traditional Chinese medicine, crusher machine has a vital role in promoting.

Crusher machine is mainly composed of steel, part of the welding process for production, for the selection of gas welding wire has strict requirements.

First, you need to consider the mechanical properties of the base metal, and then you should also consider the force of the weldment. For the weldment with high strength requirements of the welded joint, we should also choose the welding wire of equal strength higher than the strength of the base metal.

For the crusher machine, one of the principles of selection of welding wire material is to meet the requirements of weldment performance, to consider the weldability of the crusher machine.

In addition to considering the strength of welding wire selection, but also consider the weld metal and base metal fusion and the uniformity of its organization, generally requires that the melting point of the welding wire should be equal to or slightly lower than the melting point of the base metal.

Otherwise, it is easy to form defects such as burn through, edge biting and slag inclusion in the process of gas welding.

When making the crusher machine workshop, the welding groove of the T-shaped joint of the beam web and wing plate in the enterprise workshop is processed by the edge planer.

Before assembly and positioning, the oxide and rust within 50mm of the web groove surface and both sides shall be removed by high-speed grinder, and the oxide rust within 100mm of the center part in the width direction of the wing plate shall be thoroughly cleaned.

According to the material and structure requirements of the workshop beam, 1.2mmH08Mn2Si copper-plated welding wire is selected as the gas welding substrate. The quality of the wire must meet the requirements of the GB-1700 standard.

In order to prevent welding cracks caused by large welding stress of the structure, the carbon content of the wire should be controlled below 0.08%. In addition, CO2+Ar mixed gas should be used in the welding of steel structure workshop of crusher machine, and the mixing ratio is 1:1.

The crusher machine workshop is very strict for the welding process. It is also because of the high technical requirements of the crusher, the emergence of crusher has greatly improved the technical level of the pharmaceutical industry.

The crusher machine as an advanced medical treatment equipment, its unique fineness advantage will inject new vitality for the development of medicine, to meet the needs of the national development of the pharmaceutical industry.

Even a crusher  machine with such strict process requirements will have some problems in the production process. These problems mainly include the following four aspects, which need your attention:

The problem of powder aggregation

The specific surface area of the drug increases significantly after ultramicro, and the surface energy is very high, so there is a strong mutual attraction and the tendency to achieve stability. In order to prevent the aggregation of powder and keep it in monodisperse state. You can adopt suitable surface treatment and packaging technology.

Technical problems existed in chemical extraction process

There are no more than two ways of pharmaceutical application: extraction and direct medicine. From the perspective of extraction, there are two problems, one is the dispersion of the powder, the other is the gelatinization problem in the extraction process, which needs to be solved by screening and optimizing the extraction process parameters (including extraction temperature, extraction time, extraction solvent type, etc.).

Technical problems in in vitro dissolution determination

From the point of view of direct drug delivery, the core problem of the preparation made of ultrafine powder is the establishment of in vitro dissolution technology. The measures to solve this problem are to screen the dissolution medium, the methodological investigation of dissolution method, and the comprehensive selection of index components.

Technical problems of pharmacodynamic verification

Pharmacodynamics is a powerful means of verifying whether the active ingredient is preserved and enhanced after crushed. It remains to be verified that crushed Chinese medicine can significantly improve its pharmacodynamic activity.

These four problems are the problems that the crusher has always existed in the continuous development process, but if these problems can be known in advance, there will be solutions to be found.

Crusher Machine can be made into high strength, high adhesion of new products. In the medicine neck, the medicine can be directly used for oral administration after being refined, thus eliminating the complicated process of decoction and so on, and greatly facilitating the patient's medication.

Moreover, studies have shown that the crushed drugs are only equivalent to one tenth of the original prescription, or even less, which can greatly save the precious resources of medicinal materials, and is of far-reaching significance to improve the health of the whole society and effectively protect the environment.

However, for the majority of customers, whether the equipment can save costs is more critical, and the crusher machine can save raw materials to a large extent.It is understood that it can be used in smaller doses to obtain the efficacy of the original prescription.

For general medicines, the crushed materials can no longer be processed by leaching, decoction, etc., which reduces the loss of active ingredients in the production process and maximizes the use of raw materials.